Q and A with Seth Roberts (Author of ANABOLIC PHARMACOLOGY)

[Seth Roberts]

Originally Posted by FLdude883

Seth, I have read numerous forums about anadrol at 50-100mg a day, well if it's the "strongest" steroid out there, why wouldn't people be ok with just taking like say 15-25mg a day, being that it's suggested to take about 25-50mg of anavar a day, sometimes less, now wouldn't it be the other way around? Is there a mg-mg difference, I'm very confused about this. Also, I have some injectable anadrol on hand, for cutting purposes stacked with test, would 12.5mg of the injectable suffice just to maintain muscle while on a low calorie diet and perhabs even build a pound or 3?

It is considered strong because it results in a lot of weight gain -- I don't think people think in terms of a mg to mg comparison. To most people, potency is determined by how much weight they gain regardless of the quality. I think one could use a lower dose of anadrol and still see decent results with less side effects. Back in the day, injectable anadrol was considered more potent (as is injectbale winstrol).

[smbarney]

seth i was thinking about a cycle of
weeks 1-8, test cyp 500mg week
and deca 400 mg week
weeks 8-14 sustanon 500-750mg a week, tapering down the last 2 weeks.

i have clomid, nolva ect on hand for pct i was just wondering what you thought

[FLdude883]

Originally Posted by Seth Roberts

It is considered strong because it results in a lot of weight gain -- I don't think people think in terms of a mg to mg comparison. To most people, potency is determined by how much weight they gain regardless of the quality. I think one could use a lower dose of anadrol and still see decent results with less side effects. Back in the day, injectable anadrol was considered more potent (as is injectbale winstrol).

So would 12.5-20mg a day be reasonable stacked with test and maybe low dose deca for cutting purposes? I have heard that anadrol can counteract cutting because of some study showing "fat storage" with use...is this true even at 12.5mg a day?

[Gabri]

Originally Posted by Seth Roberts

I think all of these (as well as others) play a role in desensitization but I think a lot of talk of desensitization is blown out of proportion. I think the biggest factors are probably myostatin, cortisol and IGF binding protein alterations but again, unless you are on extreme doses, I don't think desenstization is a huge concern. More reason to use more moderate doses.

Thank you for the answer Seth.
This is an interesting and important factor to study in depth.....

[Seth Roberts]

Originally Posted by smbarney

seth i was thinking about a cycle of
weeks 1-8, test cyp 500mg week
and deca 400 mg week
weeks 8-14 sustanon 500-750mg a week, tapering down the last 2 weeks.

i have clomid, nolva ect on hand for pct i was just wondering what you thought

Looks like a solid cycle. The only thing I might change is to taper with cyp as opposed to the sustanon because sustanon has a reputation for not producing even blood levels. I have not seen any proof of this but why chance it.

[Chong Li]

Originally Posted by Seth Roberts

Not really an answerable question. Most docs would not find 358 to be low, just at the low end of normal unless your free test levels are low. What are your goals?

thanks for answering my question Seth.
my goals are to put on a few lbs of PERManent muscle per cycle (no water weight). i ran a TRT course for about 7 months and i looked and felt great (150mg a week-200mg a week). i lost most of it when i came off that. i recovered very well after that TRT with clomid and HCg and adex, and about 2-3 weeks after my PCT was done, my total test was 840ng/dl. I was pleased. (who knows how long it will stay there though).

since that, i changed my idea to do small short cycles throughout the year. I think the safety issue comes into play witht he PCT meds, as i would be using them more often with short cycles. I am not scared of test, but i am scared of all the orals needed to come off test with your PCT.

[bill2]

Originally Posted by Seth Roberts

You have nine week sof enanthat eat 500 per week and 7 weeks or prop at 500 mg. Looks like a 16 weeker to me. If you use the prop on the back end, you will lose some of the water weight you gain on the enanthate.

thanks for the reply but again i only have 14 amps of test prop at 100 mg per ampule...so..what gives? how i can combine them with the test enath for best results? thanks again..

[smbarney]

Originally Posted by Seth Roberts

Looks like a solid cycle. The only thing I might change is to taper with cyp as opposed to the sustanon because sustanon has a reputation for not producing even blood levels. I have not seen any proof of this but why chance it.

for pct on a cycle like that how would the following look for pct
liquid clomid 100/50/50/50 ed
liquid nolva 40/20/20/20 ed

also i had a ? about the liquid pct do i just put it under my tongue or swallow?

[Seth Roberts]

Originally Posted by FLdude883

So would 12.5-20mg a day be reasonable stacked with test and maybe low dose deca for cutting purposes? I have heard that anadrol can counteract cutting because of some study showing "fat storage" with use...is this true even at 12.5mg a day?

If you have a link to that study I would like to see it. There is a study showing decreased adiposity with anadrol in older men. I think it gives the impression of counteracting cutting because of the bloating that usually accompanies its use. Anadrol, like some other orals, decreases TBG levels which results in increased T3 uptake. This would result in increased fat burning -- at least until the body decreases T3 output. 12.5 mg of anadrol would probably still be effective (of course less so than 50 mg) but with a lot less side effects and bloating.

[Seth Roberts]

Originally Posted by Chong Li

thanks for answering my question Seth.
my goals are to put on a few lbs of PERManent muscle per cycle (no water weight). i ran a TRT course for about 7 months and i looked and felt great (150mg a week-200mg a week). i lost most of it when i came off that. i recovered very well after that TRT with clomid and HCg and adex, and about 2-3 weeks after my PCT was done, my total test was 840ng/dl. I was pleased. (who knows how long it will stay there though).

since that, i changed my idea to do small short cycles throughout the year. I think the safety issue comes into play witht he PCT meds, as i would be using them more often with short cycles. I am not scared of test, but i am scared of all the orals needed to come off test with your PCT.

You would have to weigh the "safety impact" of PCT meds against the safety impact of staying on long term. I prefer longer cycles of 12 to 16 weeks which should allow a person to do two cycles per year with enough time off to recover provided the doses are moderate. I look at PCT as coaxing/aiding the body to recover rather than forcing it to recover. I think some people see it as the latter and this usually results in issues.

[Seth Roberts]

Originally Posted by bill2

thanks for the reply but again i only have 14 amps of test prop at 100 mg per ampule...so..what gives? how i can combine them with the test enath for best results? thanks again..

Sorry about that -- I must have been distracted. You could do it many different ways. You could jump start your cycle by taking two or three doses of 100 mg per week overlapped with your enanthat in the beggining pf the cycle. Or you could start with prop and end with enanthate. Since I like longer cycles, I would probably tack the prop on at the beginning or end at 450 mg per week to make a 12 week cycle length. My preference would be at the end of the cycle to bleed off some of the water retention from enanthate while maintaining the anabolism.

[Seth Roberts]

Originally Posted by smbarney

for pct on a cycle like that how would the following look for pct
liquid clomid 100/50/50/50 ed
liquid nolva 40/20/20/20 ed

also i had a ? about the liquid pct do i just put it under my tongue or swallow?

That is pretty standard PCT. I would just swallow the liquids. Sublingual absorption gets in faster but might alter the pharmacokinetics and result in a shorter half-life.

[FLdude883]

Thank you very much seth, it's nice to get a real answer from a real professional, instead of hearing all this other bs this and bs that, I shall stack that with my test, npp, and var, thanks again sir.

[SMiller23]

Mr. Roberts, I am a huge fan of your Anabolic Pharmacology articles in MD. What can you tell me about 4-chloro-17-a-methyl-andro-4-ene-3, 17 bdiol? Is this something that is very similar to the old Halodrol-50? What are some cautionary procedures? (milk thistle and so on) Every bit of information provided will be much appreciated. Thank you for all the hard work and research you put into every article.

[stanley80]

Hey Seth, Im on my first cycle ever. Consists of sustanon 250, 500mgs a week split up tues/sat. I plan to do it 8 weeks but have enough to go 12 what do you recommend?

[gazgazo]

Hi Seth,

First of all, thank you very much for answering each question in detail. Your thread is extremely helpful.

Now onto my question. Let's say someone wants to do a somewhat modest cycle with Test C at 600 mg/week and injectable Winny at 300 mg/week for a 10 week period. He also has some Deca on hand that would give 200 mg/week for the duration of the cycle. Is it worth adding the Deca for anabolism and joint protection? Let's assume this person is also very prone to gyno and had signs of progesterone related gyno when he used tren in the past. Do you recommend using Deca (and perhaps add Caber to combat prolactin) in this circumstance or forgetting it all together?

Thank you.

[Seth Roberts]

Originally Posted by SMiller23

Mr. Roberts, I am a huge fan of your Anabolic Pharmacology articles in MD. What can you tell me about 4-chloro-17-a-methyl-andro-4-ene-3, 17 bdiol? Is this something that is very similar to the old Halodrol-50? What are some cautionary procedures? (milk thistle and so on) Every bit of information provided will be much appreciated. Thank you for all the hard work and research you put into every article.

As far as I know, this is the compound that was in the original halodrol. Milk thistle is a good precautionary measure. Of course, laying off alcohol is a very good idea. This compound is fairly benign because it does not convert to estrogen and has low androgenic sides. As a prohormone, it is not going to be terribly effective because only a small percentage is goign to convert to the 17-one and large doses are not going to be a good idea due to the methylation.

[Seth Roberts]

Originally Posted by stanley80

Hey Seth, Im on my first cycle ever. Consists of sustanon 250, 500mgs a week split up tues/sat. I plan to do it 8 weeks but have enough to go 12 what do you recommend?

I usually prefer longer cycles. Since this is your first cycle you do not know how you are going to react so you should let your body decide. If, after 8 weeks, you are not experiencing side effects then you might consider running it out to 12 weeks.

[Seth Roberts]

Originally Posted by gazgazo

Hi Seth,

First of all, thank you very much for answering each question in detail. Your thread is extremely helpful.

Now onto my question. Let's say someone wants to do a somewhat modest cycle with Test C at 600 mg/week and injectable Winny at 300 mg/week for a 10 week period. He also has some Deca on hand that would give 200 mg/week for the duration of the cycle. Is it worth adding the Deca for anabolism and joint protection? Let's assume this person is also very prone to gyno and had signs of progesterone related gyno when he used tren in the past. Do you recommend using Deca (and perhaps add Caber to combat prolactin) in this circumstance or forgetting it all together?

Thank you.

I do not recommend using something to lower prolactin unless you know that your prolactin levels are elevated (meaning a blood test). I have seen little evidence of prolactin induced gyno and it is a source of frustration for me that people tie so-called "progesterone" action with suspected elevated prolactin. A large majority of gyno can be explained simply through the disruption of the estrogen/androgen ratio. If you are prone to gyno then the liklihood is that it will worsen with future cycles. Hair loss and gyno are almost certainties if you use AAS long enough -- unless you are very lucky. In the instance that you mentioned, I would be concerned about two things 1) estrogen conversion from testosterone 2) reduced androgenicity from conversion of nandrolone to less potent 5-alpha reduced metabolites. Hopefully #2 would be overcome through the conversion of test to DHT and the addition of the winstrol, but that is not a certainty. If it were me, I would consider adding the deca and probably a SERM during the cycle.

[Gabri]

Seth, what do you think about Proviron during and post cycle as light antiestrogen and to lower SHBG? Could be an useful addiction or it is ovverrated now?
Thanks

[Seth Roberts]

Originally Posted by Gabri

Seth, what do you think about Proviron during and post cycle as light antiestrogen and to lower SHBG? Could be an useful addiction or it is ovverrated now?
Thanks

I think it is largely over-rated. People used to think (myself included) that it was useful in displacing stronger anabolics from SHBG but I am not of that opinion anymore. If you want an antiestrogen there are better choices and of course it is almost worthless as an anabolic.

[gazgazo]

Originally Posted by Seth Roberts

I do not recommend using something to lower prolactin unless you know that your prolactin levels are elevated (meaning a blood test). I have seen little evidence of prolactin induced gyno and it is a source of frustration for me that people tie so-called "progesterone" action with suspected elevated prolactin. A large majority of gyno can be explained simply through the disruption of the estrogen/androgen ratio. If you are prone to gyno then the liklihood is that it will worsen with future cycles. Hair loss and gyno are almost certainties if you use AAS long enough -- unless you are very lucky. In the instance that you mentioned, I would be concerned about two things 1) estrogen conversion from testosterone 2) reduced androgenicity from conversion of nandrolone to less potent 5-alpha reduced metabolites. Hopefully #2 would be overcome through the conversion of test to DHT and the addition of the winstrol, but that is not a certainty. If it were me, I would consider adding the deca and probably a SERM during the cycle.

Seth,

Thank you for your reply. I have one more question. I have read on several boards that taking Nolva and Deca at the same time is a no-no. Is this just bro logic? From what you said, I understand running Nolva with Deca shouldn't cause a problem. Just wanted to confirm.

Thanks.

[Seth Roberts]

Originally Posted by gazgazo

Seth,

Thank you for your reply. I have one more question. I have read on several boards that taking Nolva and Deca at the same time is a no-no. Is this just bro logic? From what you said, I understand running Nolva with Deca shouldn't cause a problem. Just wanted to confirm.

Thanks.

People have read some articles where tamoxifen increases progesterone receptors in the breast and tied that to the progestational activity of nandrolone and created a brolore nightmare. These same people advocate running a potent dopaminergic drug like cabergoline to suppress prolactin levels without any actual evidence of elevation. Unfortunately there is a lot of misinformation out there. The fact is, these drugs can cause complex changes in multiple hormone systems so noone can offer a guarantee on anything.