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Fragment 176-191

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  • Fragment 176-191

    has anyone had any experience with it? how much to take and when? do you reconstitute in bac water?
    I am the way, the truth, and the life: no man comes to the Father, but by Me.
    JESUS THE CHRIST

  • #2
    U r fucking crazy what wont you do
    "Anyone can speak english when in might get you a little strange lol"

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    • #3
      ^^^ weird stuff. First time hearing about it. What is it supposed to do to your body exactly?

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      • #4
        Originally posted by the-unnatural View Post
        ^^^ weird stuff. First time hearing about it. What is it supposed to do to your body exactly?
        The Fragment is a modified form of amino acids 176-191 of the (GH) polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, the fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

        In laboratory tests on fat cells from rodents, pigs, dogs, and humans, the fragment released fat specifically from obese fat cells but not from lean ones, reduced new fat accumulation in all fat cells, enhanced the burning of fat. In rodents (rats and mice), fragment reduced body fat in obese animals but, enhanced fat burning without changing food consumption or inducing growth (as it does not increase IGF levels) or any other unwanted Growth Hormone effect.

        In summary, fragment 176-191:

        Reduces the most stubborn abdominal fat.

        Increases muscle mass

        Increases IGF-1 levels, in an effective manner, thus making this a peptide that burns fat

        Increases energy expenditure

        Improves lipid profiles and lipolytic activity does not negatively impact blood glucose level, nor does cell proliferation occur, like GH

        Extremely potent and effective fat burner.

        In my clinic a dosage of 500mcg the ( fragment 176-191) daily for 30 days did show a reduction of body fat in the mid abdominal area in both obese, over-weight, and average built people.


        AOD9604 is a 15-mer peptide fragment(AA171 to AA191) of the C-terminus of gh to which a tyrosine is added at the N-terminal end. AOD9604 is more effective than AOD9401 in its ability to stimulate lipolytic and anti-lipogenic activity. Metabolic is developing AOD-9604 for the potential treatment of obesity.


        Fragment 176-191 is an analog of the growth hormone-releasing factor (GRF) which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of GH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.


        These segments of the synthetic peptide 176-191 have been investigated for their in vivo effects in laboratory mice Mus musculus. Results have shown that 176-191 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978). Also, this fragment, being a region of high accessibility to proteases and also rich in proline, have been demonstrated to affect the conformational change in the cytoplasmic domain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformational changes be serving as sites for peripheral protein binding in some body cells (Low et al. 1984).
        In another study of Ng et al. (2000) on animal subjects, they found out that a 500mcg dosage of the said hormone increased the lipolytic activity in adipose tissues without having negative influence in the blood glucose level. Furthermore, though it behaves like (GH), it does not causes hyperglycemia because it does not compete with GH receptors (Wu et al. 1993). Because of such effects, researchers have suggested that it might be used for the elimination of excess abdominal fat which is a significant aspect of HIV-associated lipodystrophy.

        The ( fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pinted to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its counterpart
        Last edited by RockyIII; September 15, 2011, 09:10 PM.
        I am the way, the truth, and the life: no man comes to the Father, but by Me.
        JESUS THE CHRIST

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        • #5
          anyone have any personal experience?????

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          • #6
            Originally posted by RockyIII View Post
            The Fragment is a modified form of amino acids 176-191 of the (GH) polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, the fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

            In laboratory tests on fat cells from rodents, pigs, dogs, and humans, the fragment released fat specifically from obese fat cells but not from lean ones, reduced new fat accumulation in all fat cells, enhanced the burning of fat. In rodents (rats and mice), fragment reduced body fat in obese animals but, enhanced fat burning without changing food consumption or inducing growth (as it does not increase IGF levels) or any other unwanted Growth Hormone effect.

            In summary, fragment 176-191:

            Reduces the most stubborn abdominal fat.

            Increases muscle mass

            Increases IGF-1 levels, in an effective manner, thus making this a peptide that burns fat

            Increases energy expenditure

            Improves lipid profiles and lipolytic activity does not negatively impact blood glucose level, nor does cell proliferation occur, like GH

            Extremely potent and effective fat burner.

            In my clinic a dosage of 500mcg the ( fragment 176-191) daily for 30 days did show a reduction of body fat in the mid abdominal area in both obese, over-weight, and average built people.


            AOD9604 is a 15-mer peptide fragment(AA171 to AA191) of the C-terminus of gh to which a tyrosine is added at the N-terminal end. AOD9604 is more effective than AOD9401 in its ability to stimulate lipolytic and anti-lipogenic activity. Metabolic is developing AOD-9604 for the potential treatment of obesity.


            Fragment 176-191 is an analog of the growth hormone-releasing factor (GRF) which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of GH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.


            These segments of the synthetic peptide 176-191 have been investigated for their in vivo effects in laboratory mice Mus musculus. Results have shown that 176-191 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978). Also, this fragment, being a region of high accessibility to proteases and also rich in proline, have been demonstrated to affect the conformational change in the cytoplasmic domain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformational changes be serving as sites for peripheral protein binding in some body cells (Low et al. 1984).
            In another study of Ng et al. (2000) on animal subjects, they found out that a 500mcg dosage of the said hormone increased the lipolytic activity in adipose tissues without having negative influence in the blood glucose level. Furthermore, though it behaves like (GH), it does not causes hyperglycemia because it does not compete with GH receptors (Wu et al. 1993). Because of such effects, researchers have suggested that it might be used for the elimination of excess abdominal fat which is a significant aspect of HIV-associated lipodystrophy.

            The ( fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pinted to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its counterpart

            MA is that u??
            "Feel ill as fuck - not sure if it is protein powder or tren?"-bigdog123

            Comment


            • #7
              I've used it. Multiple times.

              First stack it with cjc w/o dac and ghrp-2. Use 300-500mcg of frag post-workout before cardio.

              Does wonders but won't do much or as much as cjc and ghrp cobmined.
              Protein Factory: The best protein quality at amazing prices

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              • #8
                ma???

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                • #9
                  Originally posted by marsab73 View Post
                  ma???

                  ?????????
                  Protein Factory: The best protein quality at amazing prices

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                  • #10
                    MA = Mike Arnold

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                    • #11
                      Originally posted by Caesar View Post
                      MA = Mike Arnold
                      Oh thank you.

                      When I was starting or with frag i read a lot about pin dats forum. I personally experimented with less than 250 but it wasn't that great. 350-500 seemed like many personal sweat spot.

                      I helps with fat loss but nothing like cjc and ghrp.

                      Sent from my Transformer Prime TF201 using Tapatalk 2
                      Protein Factory: The best protein quality at amazing prices

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                      • #12
                        It's totally worthless.

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                        • #13
                          Originally posted by obeast View Post
                          It's totally worthless.
                          Please do explain
                          Protein Factory: The best protein quality at amazing prices

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