Tweet
Originally posted by str8flexed
View Post
- CarpeDiem
-
Hey Layne! Enjoyed the last post on maximum protein absorption because I always wondered where the science behind that came from. Anywho, I saw this post and I was wondering what your take is on Xtend during workouts because I wasn't sure if this post was in regards to the previous post on meal timing or just BCAA's in general?? I tend to sip on it throughout my workout and have noticed being less tired towards the end of my workout, but is this a bad idea?? Thanks for your time, hope all is well.
- CarpeDiem -
Layne,
2 Questions:
1. What are your thoughts on Diet Soda when cutting? I have heard mixed reviews, some say its totally fine to drink when cutting and some say to stay away, what do you think?
2. Do you think http://waldenfarms.com/ products are ok to use when cutting? They say that their peanut butter spread and fruit spread is calorie free. What do you think?"Strongman is an external view of how pissed off I really am at the world."Comment
-
Sounds great! Thanks for the help!!"Strongman is an external view of how pissed off I really am at the world."Comment
-
he does not have set macro ratios that everyone should follow.Originally posted by zeneise View PostComment
-
I was just about to ask the same thing, Layne. I'm starting a 12-week cut tomorrow and thought I'd try out your approach. Anything different from then (when you wrote the article) to now?Originally posted by rockhard View PostComment
-
Hi Layne,
I don't know if my question was just accidentally skipped over, but I just wanted to know if the post about sipping on BCAA refers to BCAA's in general or just in reference to meal timing. Because I sip on Xtend during my workout and just wanted to know if this is a good or bad idea??
Thanks for your time Layne,
CarpeDiemComment
-
yea it was an accident. I know I say this alot but please realize; I get over 150 emails per day, I'm in grad school, I'm trying to plan a wedding, filming a DVD, my show, writing a book, I don't get paid for this thread, I am doing my best to keep up with the questions. Just doing the best I can.
I was referring to people who sip BCAAs throughout the day, sipping during a workout is short term, only about an hour or so, I don't really see a problem with itComment
-
Hey Layne, no worries, sorry if that came off rude lol. Didn't know you were writing a book, can't wait to pick that up when it comes out. Goodluck with all those endeavors and can't wait for the next video of the series on bb.com. Thanks again for your reply Layne, your help is always greatly appreaciated!
- CarpeDiemComment
-
yup no problemComment
-
If you get a minute to give your input on this one, it would be appreciated.
2 studies here on mixed muscle FSR.
Aging does not impair the anabolic response to a protein-rich meal.
Symons TB, Schutzler SE, Cocke TL, Chinkes DL, Wolfe RR, Paddon-Jones D.
Division of Rehabilitation Sciences, The University of Texas Medical Branch, Galveston, TX 77555-1144, USA.
BACKGROUND: Sarcopenia is a debilitating condition afflicting the elderly that may be facilitated by insufficient or ineffectual intake of dietary protein. We previously showed that free-form essential amino acids acutely stimulate muscle protein synthesis in both the young and the elderly. However, the ability of an actual protein-rich food to stimulate anabolism in the young and the elderly has not been explored. OBJECTIVE: We aimed to characterize changes in plasma amino acid concentrations and to quantify muscle protein synthesis in healthy young (41 +/- 8 y old; n = 10) and elderly (70 +/- 5 y old; n = 10) persons after ingestion of a 113-g (4-oz) serving of lean beef. DESIGN: Venous blood samples and vastus lateralis muscle biopsy samples were obtained during a primed (2.0 mumol/kg) constant infusion (0.08 mumol.kg(-1).min(-1)) of l-[ring-(13)C(6)] phenylalanine. Plasma amino acid concentrations were measured and a mixed-muscle fractional synthesis rate (FSR) was calculated during the premeal period and for 5 h after beef ingestion. RESULTS: Mixed-muscle FSR increased by approximately 51% in both the elderly (mean +/- SE measurements: 0.072 +/- 0.004%/h and 0.108 +/- 0.006%/h before and after the meal, respectively) and the young (0.074 +/- 0.005%/h and 0.113 +/- 0.005%/h before and after the meal, respectively) after beef ingestion (P < 0.001). Plasma amino acid concentrations peaked at approximately 100 min after beef ingestion in both age groups but were substantially higher in the elderly (2185 +/- 134 nmol/mL compared with 1403 +/- 96 nmol/mL; P < 0.001). CONCLUSION: Despite differences in the concentration of amino acids in the plasma precursor pool, aging does not impair the ability to acutely synthesize muscle protein after ingestion of a common protein-rich food.
AND
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein.
Paddon-Jones D, Sheffield-Moore M, Katsanos CS, Zhang XJ, Wolfe RR.
Department of Surgery, The University of Texas Medical Branch, and Shriners Hospitals for Children, Galveston, Texas 77550, USA. djpaddon@utmb.edu
To counteract the debilitating progression of sarcopenia, a protein supplement should provide an energetically efficient anabolic stimulus. We quantified net muscle protein synthesis in healthy elderly individuals (65-79 yrs) following ingestion of an isocaloric intact whey protein supplement (WY; n=8) or an essential amino acid supplement (EAA; n=7). Femoral arterio-venous blood samples and vastus lateralis muscle biopsy samples were obtained during a primed, constant infusion of L-[ring-2H5]phenylalanine. Net phenylalanine uptake and mixed muscle fractional synthetic rate (FSR) were calculated during the post-absorptive period and for 3.5 h following ingestion of 15 g EAA or 15 g whey. After accounting for the residual increase in the intracellular phenylalanine pool, net post-prandial phenylalanine uptake was 53.4+/-9.7 mg phe leg-1 (EAA) and 21.7+/-4.6 mg phe leg-1 (WY), (P<0.05). Postabsorptive FSR values were 0.056+/-0.004% h-1 (EAA) and 0.049+/-0.006% h-1 (WY), (P>0.05). Both supplements stimulated FSR (P<0.05), but the increase was greatest in the EAA group with values of 0.088+/-0.011% h-1 (EAA) and 0.066+/-0.004% h-1 (WY), (P<0.05). While both EAA and WY supplements stimulated muscle protein synthesis, EAAs may provide a more energetically efficient nutritional supplement for elderly individuals.
compared to beef
Mixed-muscle FSR increased by approximately 51% in both the elderly (mean +/- SE measurements: 0.072 +/- 0.004%/h and 0.108 +/- 0.006%/h before and after the meal, respectively) and the young (0.074 +/- 0.005%/h and 0.113 +/- 0.005%/h before and after the meal, respectively) after beef ingestion (P < 0.001).
is mixed muscle FSR increased greater from a beef meal than whey or EAA's? So this is 2 separate studies but is beef showing better muscle protein synthesis with these greater values in FSR rates?
EAA group
0.088+/-0.011% h-1
Whey group
0.066+/-0.004% h-1
Beef Meal (elderly)
0.072 +/- 0.004%/h before to 0.108 +/- 0.006%/h after
Beef Meal (young)
0.074 +/- 0.005%/h before to 0.113 +/- 0.005%/h afterComment
-
you cannot compare FSR rates from seperate studies. There was a study done on this recently that showed qualitative comparisons are ok (changes from fasted to fed) but comparing absolute rates has too much error.
in short, don't compare them. do you know if they all used the same tracer? same infusion/dose protocol? how did the homogenize the tissue? what column did the use for the GCMS?
there are too many variables to make comparisonsComment
Comment